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Chemistry is the perfect vehicle for a new game of Fluxx. Elements are the perfect Keepers and combining them to reach goals just makes sense!
If the Goal is Salt (AKA: Sodium Chloride), naturally you'll need the Keepers Sodium and Chlorine. Plus, Chemistry Fluxx has one of the coolest Rules of all time: Helium Effect.
When the Helium Effect Rule is in play, whoever has the Helium Keeper has to talk in a high squeaky voice.